Reactome | Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-443900] Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] - Rattus norvegicus [Complex:R-RNO-432098] Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-432096] Activated integrin alphaIIb beta3 binds SHC1 - Rattus norvegicus [Reaction:R-RNO-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10130033
displayName	Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane]
hasComponent	[Complex:R-RNO-377608] Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] [Complex:R-RNO-354176] Talin:RIAM complex [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] - Homo sapiens
maxDepth	6
name	Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex
producedByEvent	[BlackBoxEvent:R-RNO-443910] SHC1 dissociates from integrin alphaIIb beta3 - Rattus norvegicus [Reaction:R-RNO-354077] Integrin alphaIIb beta3 activation - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-354130
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-RNO-443910] SHC1 dissociates from integrin alphaIIb beta3 [Reaction:R-RNO-354077] Integrin alphaIIb beta3 activation
(input)	[Reaction:R-RNO-432096] Activated integrin alphaIIb beta3 binds SHC1 [Reaction:R-RNO-354149] Interaction of integrin alphaIIb beta3 with Fibrinogen
(hasComponent)	[Complex:R-RNO-432098] Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] [Complex:R-RNO-443900] Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] [Complex:R-RNO-354137] Focal complex [plasma membrane]
(inferredTo)	[Complex:R-HSA-354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane]