Reactome | p-S15-TP53 Tetramer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-3786257] p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-6805285] PLK3 phosphorylates TP53 - Rattus norvegicus [Reaction:R-RNO-6799246] CHEK1 phosphorylates TP53 - Rattus norvegicus [Reaction:R-RNO-69685] CHEK2 phosphorylates TP53 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10103973
displayName	p-S15-TP53 Tetramer [nucleoplasm]
hasComponent	4 × [EntityWithAccessionedSequence:R-RNO-69507] phospho-p-S15-TP53 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-349474] p-S15-TP53 Tetramer [nucleoplasm] - Homo sapiens
maxDepth	2
name	p-S15-TP53 Tetramer
positivelyRegulates	[PositiveRegulation:10173739] Positive regulation by 'p-S15-TP53 Tetramer [nucleoplasm]'
producedByEvent	[Reaction:R-RNO-5693609] ATM phosphorylates TP53 at S15 - Rattus norvegicus [Reaction:R-RNO-6799332] ATR phosphorylates TP53 - Rattus norvegicus [Reaction:R-RNO-6805470] AMPK phosphorylates TP53 - Rattus norvegicus [Reaction:R-RNO-6805479] TP53RK phosphorylates TP53 - Rattus norvegicus [Reaction:R-RNO-264435] Dissociation of the COP1-p53 complex - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-349474
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[PositiveRegulation:10173739] Positive regulation by 'p-S15-TP53 Tetramer [nucleoplasm]'
(hasComponent)	[Complex:R-RNO-3786257] p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm] [Complex:R-RNO-349420] p-S387-RFWD2:p-S15-TP53 [nucleoplasm]
(input)	[Reaction:R-RNO-6805285] PLK3 phosphorylates TP53 [Reaction:R-RNO-6799246] CHEK1 phosphorylates TP53 [Reaction:R-RNO-69685] CHEK2 phosphorylates TP53
(output)	[Reaction:R-RNO-6805470] AMPK phosphorylates TP53 [Reaction:R-RNO-6805479] TP53RK phosphorylates TP53 [Reaction:R-RNO-5693609] ATM phosphorylates TP53 at S15 [Reaction:R-RNO-264435] Dissociation of the COP1-p53 complex [Reaction:R-RNO-6799332] ATR phosphorylates TP53
(inferredTo)	[Complex:R-HSA-349474] p-S15-TP53 Tetramer [nucleoplasm]