Reactome | DHX9 binds DNA

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10169188
displayName	DHX9 binds DNA
eventOf	[Pathway:R-RNO-3134963] DEx/H-box helicases activate type I IFN and inflammatory cytokines production - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-3134953] DHX36 or DHX9 binds MyD88 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-3134954] DHX9 binds DNA - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-847700] Dhx9 [cytosol] [OtherEntity:R-ALL-3134861] Unmethylated CpG DNA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	DHX9 binds DNA
output	[Complex:R-RNO-3134960] DHX9:CpG [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3134954
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-3134963] DEx/H-box helicases activate type I IFN and inflammatory cytokines production
(precedingEvent)	[Reaction:R-RNO-3134953] DHX36 or DHX9 binds MyD88
(inferredTo)	[Reaction:R-HSA-3134954] DHX9 binds DNA