Reactome | THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1

Schema > Reaction > Entries

THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10129224
displayName	THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1
eventOf	[Pathway:R-RNO-216083] Integrin cell surface interactions - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-265429] THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 - Homo sapiens
input	[DefinedSet:R-RNO-4205068] Integrin alpha3beta1, alpha4beta1 [plasma membrane] [Complex:R-RNO-265405] THBS1 trimer [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1
output	[Complex:R-RNO-265407] Integrin alpha3beta1, alpha4beta1:THBS1 trimer [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-265429
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-216083] Integrin cell surface interactions
(inferredTo)	[Reaction:R-HSA-265429] THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1

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