Reactome | Translocation of COP1 from the nucleus to the cytoplasm

Schema > Reaction > Entries

Translocation of COP1 from the nucleus to the cytoplasm Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10128902
displayName	Translocation of COP1 from the nucleus to the cytoplasm
eventOf	[Pathway:R-RNO-349425] Autodegradation of the E3 ubiquitin ligase COP1 - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-264444] Autoubiquitination of phospho-COP1(Ser-387 ) - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-264418] Translocation of COP1 from the nucleus to the cytoplasm - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-349450] phospho-Cop1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of COP1 from the nucleus to the cytoplasm
output	[EntityWithAccessionedSequence:R-RNO-349439] phospho-Cop1 [cytosol]
precedingEvent	[Reaction:R-RNO-349444] Phosphorylation of COP1 at Ser-387 by ATM - Rattus norvegicus [Reaction:R-RNO-264435] Dissociation of the COP1-p53 complex - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-264418
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-349425] Autodegradation of the E3 ubiquitin ligase COP1
(precedingEvent)	[Reaction:R-RNO-264444] Autoubiquitination of phospho-COP1(Ser-387 )
(inferredTo)	[Reaction:R-HSA-264418] Translocation of COP1 from the nucleus to the cytoplasm

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