Reactome | Formation of Senescence-Associated Heterochromatin Foci (SAHF)

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224579
displayName	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
eventOf	[Pathway:R-RNO-2559586] DNA Damage/Telomere Stress Induced Senescence - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-3878123] Initiation of SAHF formation - Rattus norvegicus [Reaction:R-RNO-4647594] SAHF formation - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-2559584] Formation of Senescence-Associated Heterochromatin Foci (SAHF) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2559584
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-2559586] DNA Damage/Telomere Stress Induced Senescence
(inferredTo)	[Pathway:R-HSA-2559584] Formation of Senescence-Associated Heterochromatin Foci (SAHF)

Cite Us!