Reactome | p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]

Schema > Complex > Entries

compartment	[Compartment:81347] chromosome, centromeric region
consumedByEvent	[Reaction:R-RNO-2467809] ESPL1 (Separase) cleaves centromeric cohesin - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10157412
displayName	p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]
hasComponent	2 × [Complex:R-RNO-375303] Microtubule-bound kinetochore [cytosol] [Complex:R-RNO-2500251] p-RAD21-Ac-Cohesin [chromosome, centromeric region] [DefinedSet:R-RNO-2468261] PDS5 [chromosome, centromeric region] [EntityWithAccessionedSequence:R-RNO-2468269] phospho-Cdca5 [chromosome, centromeric region] 2 × [OtherEntity:R-ALL-1638792] Sister Centromere [chromosome] [EntityWithAccessionedSequence:R-RNO-2577088] Wapl [chromosome, centromeric region]
inDisease	false
inferredFrom	[Complex:R-HSA-2500242] p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Homo sapiens
maxDepth	8
name	p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules
producedByEvent	[Reaction:R-RNO-1638821] PP2A-B56 dephosphorylates centromeric cohesin - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2500242
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-RNO-1638821] PP2A-B56 dephosphorylates centromeric cohesin
(input)	[Reaction:R-RNO-2467809] ESPL1 (Separase) cleaves centromeric cohesin
(inferredTo)	[Complex:R-HSA-2500242] p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region]

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