Reactome | FSTL3 binds Activin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10167142
displayName	FSTL3 binds Activin
eventOf	[Pathway:R-RNO-2473224] Antagonism of Activin by Follistatin - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2473186] FSTL3 binds Activin - Homo sapiens
input	[DefinedSet:R-RNO-2470494] Activin A,AB,B [extracellular region] 2 × [EntityWithAccessionedSequence:R-RNO-2473199] Fstl3 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	FSTL3 binds Activin
output	[Complex:R-RNO-2473219] Activin A,AB,B:FSTL3 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2473186
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-2473224] Antagonism of Activin by Follistatin
(inferredTo)	[Reaction:R-HSA-2473186] FSTL3 binds Activin