Reactome | Clathrin:AP2 complex [clathrin-coated endocytic vesicle membrane]

Schema > Complex > Entries

compartment	[Compartment:24339] clathrin-coated endocytic vesicle membrane
componentOf	[Complex:R-RNO-8855135] VLDL:PCSK9:Clathrin:AP2 [lysosomal membrane] - Rattus norvegicus [Complex:R-RNO-6784728] PCSK9:LDLR:Clathrin:AP2 [endolysosome membrane] - Rattus norvegicus [Complex:R-RNO-2130331] Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10163904
displayName	Clathrin:AP2 complex [clathrin-coated endocytic vesicle membrane]
hasComponent	[Complex:R-RNO-2130637] Adaptor protein 2 complex [endolysosome membrane] [Complex:R-RNO-2130407] Clathrin [clathrin-coated endocytic vesicle membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-2130671] Clathrin:AP2 complex [clathrin-coated endocytic vesicle membrane] - Homo sapiens
maxDepth	4
name	Clathrin:AP2 complex
producedByEvent	[Reaction:R-RNO-2130486] Uncoating of clathrin-coated vesicles and fusion with endosomes - Rattus norvegicus [BlackBoxEvent:R-RNO-6784738] Degradation of PCSK9:LDLR:Clathrin-coated vesicle - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2130671
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-RNO-2130486] Uncoating of clathrin-coated vesicles and fusion with endosomes [BlackBoxEvent:R-RNO-6784738] Degradation of PCSK9:LDLR:Clathrin-coated vesicle
(hasComponent)	[Complex:R-RNO-2130331] Clathrin coated MHC class II alpha/beta/Ii nonamer [clathrin-coated endocytic vesicle membrane] [Complex:R-RNO-6784728] PCSK9:LDLR:Clathrin:AP2 [endolysosome membrane] [Complex:R-RNO-8855135] VLDL:PCSK9:Clathrin:AP2 [lysosomal membrane]
(inferredTo)	[Complex:R-HSA-2130671] Clathrin:AP2 complex [clathrin-coated endocytic vesicle membrane]