Reactome | Integrin alphaVbeta3 [plasma membrane]

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Integrin alphaVbeta3 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-265408] Integrin alphaVbeta3:IBSP [plasma membrane] - Rattus norvegicus [Complex:R-RNO-4086146] DMP1:Integrin alphVbeta3 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-265427] Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) - Rattus norvegicus [Reaction:R-RNO-265426] Interaction of integrin alphaVbeta3 with Tenascin - Rattus norvegicus [Reaction:R-RNO-265423] Interaction of integrin alphaVbeta3 with Fibrillin - Rattus norvegicus [Reaction:R-RNO-5218818] Integrin alphaVbeta3 binds p-6Y-VEGFR2 - Rattus norvegicus [Reaction:R-RNO-4086200] Dentin matrix protein 1 binds integrin alphaVbeta3 - Rattus norvegicus [Reaction:R-RNO-4088218] Tetrastatin binds integrin alphaVbeta3 - Rattus norvegicus [Reaction:R-RNO-210304] Interaction of integrin alphaVbeta3 with PECAM1 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10127833
displayName	Integrin alphaVbeta3 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-210013] Itgav [plasma membrane] [EntityWithAccessionedSequence:R-RNO-57600] ITGB3 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-210216] Integrin alphaVbeta3 [plasma membrane] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-RNO-2681746] Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] - Rattus norvegicus [DefinedSet:R-RNO-2466235] Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] - Rattus norvegicus [DefinedSet:R-RNO-4205071] Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] - Rattus norvegicus
name	Integrin alphaVbeta3
positivelyRegulates	[PositiveRegulation:10219023] Positive regulation by 'Integrin alphaVbeta3 [plasma membrane]'
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-210216
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasMember)	[DefinedSet:R-RNO-2681746] Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] [DefinedSet:R-RNO-2466235] Integrins alphaVbeta1, alphaVbeta3, alphaVbeta5, alpha2bbeta3 [plasma membrane] [CandidateSet:R-RNO-2731104] Integrin alpha2beta1, (alpha6beta4) [plasma membrane] [DefinedSet:R-RNO-2396352] Fibrilin-binding integrins [plasma membrane] [DefinedSet:R-RNO-374573] Integrins [plasma membrane] [DefinedSet:R-RNO-4088270] Integrins alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [plasma membrane] [DefinedSet:R-RNO-4205071] Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] [DefinedSet:R-RNO-4085052] Integrins alphaVbeta3, alpha3beta1 [plasma membrane] [DefinedSet:R-RNO-4085079] Integrins alphaVbeta3, alphaVbeta5 [plasma membrane] [DefinedSet:R-RNO-2426294] Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] [DefinedSet:R-RNO-4205072] Integrin alphaVbeta3, 5, 8 [plasma membrane] [DefinedSet:R-RNO-2396176] LAP1 binding-integrins [plasma membrane] [DefinedSet:R-RNO-2396408] LAP3-binding integrins [plasma membrane]
(input)	[Reaction:R-RNO-4086200] Dentin matrix protein 1 binds integrin alphaVbeta3 [Reaction:R-RNO-265427] Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) [Reaction:R-RNO-265426] Interaction of integrin alphaVbeta3 with Tenascin [Reaction:R-RNO-265423] Interaction of integrin alphaVbeta3 with Fibrillin [Reaction:R-RNO-4088218] Tetrastatin binds integrin alphaVbeta3 [Reaction:R-RNO-210304] Interaction of integrin alphaVbeta3 with PECAM1 [Reaction:R-RNO-5218818] Integrin alphaVbeta3 binds p-6Y-VEGFR2
(hasComponent)	[Complex:R-RNO-4086146] DMP1:Integrin alphVbeta3 [plasma membrane] [Complex:R-RNO-265408] Integrin alphaVbeta3:IBSP [plasma membrane] [Complex:R-RNO-265412] Integrin alphaVbeta3:Tenascin [plasma membrane] [Complex:R-RNO-265416] Integrin alphaVbeta3:Fibrillin-1 [plasma membrane] [Complex:R-RNO-4088257] Tetrastatin:Integrin alphaVbeta3 [plasma membrane] [Complex:R-RNO-210229] Integrin alphaVbeta3:PECAM1 [plasma membrane] [Complex:R-RNO-5218779] VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3 [plasma membrane]
(regulator)	[PositiveRegulation:10219023] Positive regulation by 'Integrin alphaVbeta3 [plasma membrane]'
(inferredTo)	[Complex:R-HSA-210216] Integrin alphaVbeta3 [plasma membrane]

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