Reactome | CHST1 transfers sulfate to Gal on keratan chain

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CHST1 transfers sulfate to Gal on keratan chain Show undefined attributes

catalystActivity	[CatalystActivity:10162945] keratan sulfotransferase activity of CHST1 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10162947
displayName	CHST1 transfers sulfate to Gal on keratan chain
eventOf	[Pathway:R-RNO-2022854] Keratan sulfate biosynthesis - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-2046180] KSPG is secreted from the cell - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2046175] CHST1 transfers sulfate to Gal on keratan chain - Homo sapiens
input	[DefinedSet:R-RNO-2046166] KSPG(1) [Golgi lumen] [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CHST1 transfers sulfate to Gal on keratan chain Further sulfation on galactose residues produces KSPG
output	[DefinedSet:R-RNO-2046288] KSPG(2) [Golgi lumen] [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-RNO-2046222] CHST2,3,5,6 transfer sulfate to GlcNAc on keratan chain - Rattus norvegicus [Reaction:R-RNO-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2046175
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2022854] Keratan sulfate biosynthesis
(precedingEvent)	[BlackBoxEvent:R-RNO-2046180] KSPG is secreted from the cell
(inferredTo)	[Reaction:R-HSA-2046175] CHST1 transfers sulfate to Gal on keratan chain

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