Reactome | Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA

Schema > Reaction > Entries

Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10143351] fatty acid elongase activity of ELOVL1,2,3,5 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10162888
displayName	Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA
eventOf	[Pathway:R-RNO-2046105] Linoleic acid (LA) metabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-2046092] Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2046094] Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-2046042] GLA-CoA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046066] Malonyl-CoA [endoplasmic reticulum lumen] 2 × [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA
output	[SimpleEntity:R-ALL-159751] CO2 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-162743] CoA-SH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046045] DGL-CoA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] 2 × [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-RNO-2046096] Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2046094
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2046105] Linoleic acid (LA) metabolism
(precedingEvent)	[Reaction:R-RNO-2046092] Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA
(inferredTo)	[Reaction:R-HSA-2046094] Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA

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