Reactome | NOSTRIN mediated eNOS trafficking

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NOSTRIN mediated eNOS trafficking Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223355
displayName	NOSTRIN mediated eNOS trafficking
eventOf	[Pathway:R-RNO-202131] Metabolism of nitric oxide: NOS3 activation and regulation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:18827] nitric oxide metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-203716] eNOS:Caveolin-1 complex binds to Nostrin - Rattus norvegicus [Reaction:R-RNO-203662] eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 - Rattus norvegicus [BlackBoxEvent:R-RNO-203625] NOSTRIN mediated translocation of eNOS from plasma membrane - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-203641] NOSTRIN mediated eNOS trafficking - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	NOSTRIN mediated eNOS trafficking
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-203641
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-202131] Metabolism of nitric oxide: NOS3 activation and regulation
(inferredTo)	[Pathway:R-HSA-203641] NOSTRIN mediated eNOS trafficking

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