Reactome | Profilin:G-actin [cytosol]

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Profilin:G-actin [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5665995] Profilin:G-actin:MKL1 [cytosol] - Rattus norvegicus [Complex:R-RNO-5665773] RHOC:GTP:FMNL3:G-actin [plasma membrane] - Rattus norvegicus [Complex:R-RNO-5665773] RHOC:GTP:FMNL3:G-actin [plasma membrane] - Rattus norvegicus [Complex:R-RNO-5665977] RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] - Rattus norvegicus [Complex:R-RNO-5665977] RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5666001] Profilin:G-actin binds MKL1 - Rattus norvegicus [Reaction:R-RNO-5665767] Activated FMNL3 binds G-actin - Rattus norvegicus [Reaction:R-RNO-5665767] Activated FMNL3 binds G-actin - Rattus norvegicus [Reaction:R-RNO-5665751] CDC42:GTP:FMNL2 binds Profilin:G-actin - Rattus norvegicus [Reaction:R-RNO-5665751] CDC42:GTP:FMNL2 binds Profilin:G-actin - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10126055
displayName	Profilin:G-actin [cytosol]
hasComponent	[Complex:R-RNO-201857] G-actin [cytosol] [CandidateSet:R-RNO-203077] PFN [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-203080] Profilin:G-actin [cytosol] - Homo sapiens
maxDepth	4
name	Profilin:G-actin
producedByEvent	[Reaction:R-RNO-203070] Association of profilin with monomeric actin - Rattus norvegicus [Reaction:R-RNO-5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments - Rattus norvegicus [Reaction:R-RNO-5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-203080
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-5665767] Activated FMNL3 binds G-actin [Reaction:R-RNO-5666001] Profilin:G-actin binds MKL1 [Reaction:R-RNO-5665751] CDC42:GTP:FMNL2 binds Profilin:G-actin
(hasComponent)	[Complex:R-RNO-5665773] RHOC:GTP:FMNL3:G-actin [plasma membrane] [Complex:R-RNO-5665977] RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] [Complex:R-RNO-5665995] Profilin:G-actin:MKL1 [cytosol] [Complex:R-RNO-5665660] RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] [Complex:R-RNO-5665752] CDC42:FMNL2:Profilin:G-actin [plasma membrane]
(output)	[Reaction:R-RNO-5665809] SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments [Reaction:R-RNO-203070] Association of profilin with monomeric actin
(inferredTo)	[Complex:R-HSA-203080] Profilin:G-actin [cytosol]

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