Reactome | Caspase mediated cleavage of beta-catenin

Schema > Reaction > Entries

Caspase mediated cleavage of beta-catenin Show undefined attributes

catalystActivity	[CatalystActivity:10124948] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10126034
displayName	Caspase mediated cleavage of beta-catenin
eventOf	[Pathway:R-RNO-351906] Apoptotic cleavage of cell adhesion proteins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-202969] Caspase mediated cleavage of beta-catenin - Homo sapiens
input	[CandidateSet:R-RNO-191727] beta-catenin [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Caspase mediated cleavage of beta-catenin
output	[EntityWithAccessionedSequence:R-RNO-202930] Ctnnb1 [cytosol] [EntityWithAccessionedSequence:R-RNO-202950] Ctnnb1 [cytosol]
precedingEvent	[Reaction:R-RNO-114252] Cleavage of Procaspase-3 by the apoptosome - Rattus norvegicus [Reaction:R-RNO-418845] Activation of caspase-3 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-202969
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-351906] Apoptotic cleavage of cell adhesion proteins
(inferredTo)	[Reaction:R-HSA-202969] Caspase mediated cleavage of beta-catenin

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