Reactome | YWHAB dimer [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-2028630] p-YAP1:YWHAB [cytosol] - Rattus norvegicus [Complex:R-RNO-5672710] 'activator' RAF:YWHAB dimer [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-2028644] YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 - Rattus norvegicus [Reaction:R-RNO-5672951] Inactive RAFs bind YWHAB - Rattus norvegicus [Reaction:R-RNO-5672954] p-S311,S406 KSR1:MARK3 binds YWHAB dimer - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10108847
displayName	YWHAB dimer [cytosol]
hasComponent	2 × [EntityWithAccessionedSequence:R-RNO-48888] Ywhab [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2028645] YWHAB dimer [cytosol] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-RNO-9614573] YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] - Rattus norvegicus [DefinedSet:R-RNO-1445138] 14-3-3 dimer [cytosol] - Rattus norvegicus
name	YWHAB dimer
producedByEvent	[Reaction:R-RNO-5672958] YWHAB dimer dissociates from KSR1:MARK3 - Rattus norvegicus [Reaction:R-RNO-5672960] YWHAB dimer dissociates from dephosphorylated RAF - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2028645
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-RNO-9614573] YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] [DefinedSet:R-RNO-1445138] 14-3-3 dimer [cytosol]
(input)	[Reaction:R-RNO-2028644] YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 [Reaction:R-RNO-5672951] Inactive RAFs bind YWHAB [Reaction:R-RNO-5672954] p-S311,S406 KSR1:MARK3 binds YWHAB dimer
(hasComponent)	[Complex:R-RNO-2028630] p-YAP1:YWHAB [cytosol] [Complex:R-RNO-5672728] dephosphorylated inactive RAFS:YWHAB dimer [cytosol] [Complex:R-RNO-5672707] inactive RAFs:YWHAB dimer [cytosol] [Complex:R-RNO-5675412] p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] [Complex:R-RNO-5675430] p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] [Complex:R-RNO-5672696] p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] [Complex:R-RNO-5672692] p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] [Complex:R-RNO-5675414] p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] [Complex:R-RNO-5672710] 'activator' RAF:YWHAB dimer [cytosol] [Complex:R-RNO-5672712] p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] [Complex:R-RNO-5672715] p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane]
(output)	[Reaction:R-RNO-5672960] YWHAB dimer dissociates from dephosphorylated RAF [Reaction:R-RNO-5672958] YWHAB dimer dissociates from KSR1:MARK3
(inferredTo)	[Complex:R-HSA-2028645] YWHAB dimer [cytosol]

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