Reactome | Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-202214] Dephosphorylation of Lck-pY505 by CD45 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10125533
displayName	Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-167542] Cd4 [plasma membrane] [Complex:R-RNO-203463] MHC Class II bearing antigen peptide [plasma membrane] [EntityWithAccessionedSequence:R-RNO-202159] phospho-p-Y505-LCK [plasma membrane] [Complex:R-RNO-198901] T-cell receptor complex [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-202154] Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] - Homo sapiens
maxDepth	6
name	Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505)
producedByEvent	[Reaction:R-RNO-202233] Inactivation of Lck by Csk - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-202154
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-202214] Dephosphorylation of Lck-pY505 by CD45
(output)	[Reaction:R-RNO-202233] Inactivation of Lck by Csk
(inferredTo)	[Complex:R-HSA-202154] Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane]

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