Reactome | BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane]

Schema > Complex > Entries

compartment	[Compartment:171062] early endosome membrane
consumedByEvent	[Reaction:R-RNO-201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10124823
displayName	BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane]
hasComponent	[Complex:R-RNO-201463] BMP2 dimer [extracellular region] [Complex:R-RNO-201465] BMPRII dimer [plasma membrane] [DefinedSet:R-RNO-201482] p-2S-SMAD1/5/8 [cytosol] [Complex:R-RNO-201447] p-4S-BMPRI dimer [plasma membrane] [EntityWithAccessionedSequence:R-RNO-201645] Zfyve16 [early endosome membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-201467] BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] - Homo sapiens
maxDepth	4
name	BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8
producedByEvent	[Reaction:R-RNO-201476] Activated type I receptor phosphorylates R-Smad1/5/8 directly - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-201467
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex
(output)	[Reaction:R-RNO-201476] Activated type I receptor phosphorylates R-Smad1/5/8 directly
(inferredTo)	[Complex:R-HSA-201467] BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane]

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