Reactome | maltose + H2O => 2 D-glucose (sucrase-isomaltase)

Schema > Reaction > Entries

maltose + H2O => 2 D-glucose (sucrase-isomaltase) Show undefined attributes

catalystActivity	[CatalystActivity:10121053] alpha-1,4-glucosidase activity of sucrase-isomaltase dimer [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10121670
displayName	maltose + H2O => 2 D-glucose (sucrase-isomaltase)
eventOf	[Pathway:R-RNO-189085] Digestion of dietary carbohydrate - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-191108] maltose + H2O => 2 D-glucose (sucrase-isomaltase) - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region] [SimpleEntity:R-ALL-188986] Mal [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	maltose + H2O => 2 D-glucose (sucrase-isomaltase) Digestion of maltose by sucrase-isomaltase to yield glucose
output	2 × [SimpleEntity:R-ALL-70115] Glc [extracellular region]
precedingEvent	[Reaction:R-RNO-188979] Digestion of linear starch (amylose) by extracellular amylase - Rattus norvegicus [Reaction:R-RNO-191114] Digestion of branched starch (amylopectin) by extracellular amylase - Rattus norvegicus [Reaction:R-RNO-189053] Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose - Rattus norvegicus [Reaction:R-RNO-191101] maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-191108
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-RNO-8932955] SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol
(hasEvent)	[Pathway:R-RNO-189085] Digestion of dietary carbohydrate
(inferredTo)	[Reaction:R-HSA-191108] maltose + H2O => 2 D-glucose (sucrase-isomaltase)

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