Reactome | Connexin oligomerization in endoplasmic reticulum membrane

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Connexin oligomerization in endoplasmic reticulum membrane Show undefined attributes

catalystActivity	[CatalystActivity:10121563] gap junction channel activity of GJB1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10121565
displayName	Connexin oligomerization in endoplasmic reticulum membrane
eventOf	[Pathway:R-RNO-190704] Oligomerization of connexins into connexons - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-190681] Connexin oligomerization in endoplasmic reticulum membrane - Homo sapiens
input	6 × [EntityWithAccessionedSequence:R-RNO-190656] Gjb1 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Connexin oligomerization in endoplasmic reticulum membrane
output	[Complex:R-RNO-190647] Connexin 32 connexon [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-190681
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-190704] Oligomerization of connexins into connexons
(inferredTo)	[Reaction:R-HSA-190681] Connexin oligomerization in endoplasmic reticulum membrane

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