Reactome | FGFR3c ligand binding and activation

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FGFR3c ligand binding and activation Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223109
displayName	FGFR3c ligand binding and activation
eventOf	[Pathway:R-RNO-190239] FGFR3 ligand binding and activation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24611] fibroblast growth factor receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-8851619] GALNT3 transfers GalNAc to FGF23 - Rattus norvegicus [BlackBoxEvent:R-RNO-8851632] GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region - Rattus norvegicus [Reaction:R-RNO-190261] FGFR3c binds to FGF - Rattus norvegicus [Reaction:R-RNO-190388] Autocatalytic phosphorylation of FGFR3c - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-190372] FGFR3c ligand binding and activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	FGFR3c ligand binding and activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-190372
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-190239] FGFR3 ligand binding and activation
(inferredTo)	[Pathway:R-HSA-190372] FGFR3c ligand binding and activation

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