Reactome | Phospho-Shc dissociates from the Trk receptor

Schema > Reaction > Entries

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:181805] Jassal, Bijay, 2006-06-20
dbId	181827
displayName	Phospho-Shc dissociates from the Trk receptor
input	[Complex:R-RNO-181824] NGF dimer:Phosphorylated Trk receptor dimer:Phospho-SHC [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:181800] Role of Shc in the activation of Ras in response to epidermal growth factor and nerve growth factor
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phospho-Shc dissociates from the Trk receptor
orthologousEvent	[Reaction:R-HSA-167217] Phospho-Shc dissociates from the TrkA receptor - Homo sapiens
output	[Complex:R-RNO-181785] NGF dimer:Trk receptor dimer [plasma membrane] [EntityWithAccessionedSequence:R-RNO-179565] Phospho-SHC [cytosol]
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-181827
summation	[Summation:189691] Once Shc is phosphorylated, it dissociates from the receptor...
updateTrackers	[UpdateTracker:9792012] Update Tracker - [Reaction:181827] Phospho-Shc dissociates from the Trk receptor - v24:[addSummation]

(updatedInstance)

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