Reactome | Conjugation of benzoate with glycine

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Conjugation of benzoate with glycine Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222701
displayName	Conjugation of benzoate with glycine
eventOf	[Pathway:R-RNO-159424] Conjugation of carboxylic acids - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-159443] benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate - Rattus norvegicus [Reaction:R-RNO-159566] benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-177135] Conjugation of benzoate with glycine - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Conjugation of benzoate with glycine
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-177135
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-159424] Conjugation of carboxylic acids
(inferredTo)	[Pathway:R-HSA-177135] Conjugation of benzoate with glycine

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