Reactome | NAT1 acetylation

Schema > Reaction > Entries

NAT1 acetylation Show undefined attributes

catalystActivity	[CatalystActivity:10119602] arylamine N-acetyltransferase activity of AcC-NAT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10119604
displayName	NAT1 acetylation
eventOf	[Pathway:R-RNO-156582] Acetylation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-174959] The acetyl group from acetyl-CoA is transferred to NAT1 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-174963] NAT1 acetylation - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-158833-3] AcC-NAT2 [cytosol] [DefinedSet:R-ALL-174969] NAT1 substrate [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NAT1 acetylation
output	[DefinedSet:R-ALL-174960] NAT1 acetylated conjugate [cytosol] [EntityWithAccessionedSequence:R-RNO-158692-3] NAT2 [cytosol]
precedingEvent	[Reaction:R-RNO-174959] The acetyl group from acetyl-CoA is transferred to NAT1 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-174963
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-156582] Acetylation
(precedingEvent)	[Reaction:R-RNO-174959] The acetyl group from acetyl-CoA is transferred to NAT1
(inferredTo)	[Reaction:R-HSA-174963] NAT1 acetylation