Reactome | SCF-beta-TrCP mediated degradation of Emi1

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SCF-beta-TrCP mediated degradation of Emi1 Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222975
displayName	SCF-beta-TrCP mediated degradation of Emi1
eventOf	[Pathway:R-RNO-176408] Regulation of APC/C activators between G1/S and early anaphase - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:3446115] regulation of mitotic cell cycle phase transition
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-174209] Phosphorylated Emi1 binds the beta-TrCP in the SCF complex - Rattus norvegicus [Reaction:R-RNO-174159] Ubiquitination of Emi1 by SCF-beta-TrCP - Rattus norvegicus [BlackBoxEvent:R-RNO-174203] SCF-mediated degradation of Emi1 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-174113] SCF-beta-TrCP mediated degradation of Emi1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SCF-beta-TrCP mediated degradation of Emi1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-174113
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-176408] Regulation of APC/C activators between G1/S and early anaphase
(inferredTo)	[Pathway:R-HSA-174113] SCF-beta-TrCP mediated degradation of Emi1

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