Reactome | C5b binds C6

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10118946
displayName	C5b binds C6
eventOf	[Pathway:R-RNO-166665] Terminal pathway of complement - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-173705] C5b binds C6 - Homo sapiens
input	[Complex:R-RNO-173671] C5b [extracellular region] [EntityWithAccessionedSequence:R-RNO-173706] C6 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	C5b binds C6
output	[Complex:R-RNO-173711] C5b:C6 [extracellular region]
precedingEvent	[Reaction:R-RNO-173680] Activation of C5 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-173705
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-166665] Terminal pathway of complement
(inferredTo)	[Reaction:R-HSA-173705] C5b binds C6