Reactome | tBID binds to inactive BAK protein

Schema > Reaction > Entries

tBID binds to inactive BAK protein Show undefined attributes

category	binding
compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10117405
displayName	tBID binds to inactive BAK protein
eventOf	[Pathway:R-RNO-111452] Activation and oligomerization of BAK protein - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-139895] tBID activates BAK protein - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-168848] tBID binds to inactive BAK protein - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-50690] BAK1 activated [mitochondrial outer membrane] [EntityWithAccessionedSequence:R-RNO-114266] Bid [mitochondrial outer membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	tBID binds to inactive BAK protein
output	[Complex:R-RNO-168847] tBID bound to inactive BAK [mitochondrial outer membrane]
precedingEvent	[Reaction:R-RNO-139920] Translocation of tBID to mitochondria - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-168848
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-111452] Activation and oligomerization of BAK protein
(precedingEvent)	[Reaction:R-RNO-139895] tBID activates BAK protein
(inferredTo)	[Reaction:R-HSA-168848] tBID binds to inactive BAK protein

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