Reactome | ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane]

Schema > Complex > Entries

compartment	[Compartment:12045] endoplasmic reticulum membrane
consumedByEvent	[Reaction:R-RNO-1678944] Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10158232
displayName	ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane]
hasComponent	2 × [SimpleEntity:R-ALL-211579] ATP [endoplasmic reticulum membrane] 2 × [EntityWithAccessionedSequence:R-RNO-1678932] Cnpy3 [endoplasmic reticulum lumen] 2 × [EntityWithAccessionedSequence:R-RNO-981545] HSP90B1 [endoplasmic reticulum lumen] 2 × [CandidateSet:R-RNO-1679009] TLR7/8/9 [endoplasmic reticulum membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-1679076] ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane] - Homo sapiens
maxDepth	3
name	ATP-bound Gp96 dimer:CNPY3:TLR7/8/9
producedByEvent	[Reaction:R-RNO-1678923] TLR folding by chaperones GP96 and CNPY3 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1679076
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-1678944] Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex
(output)	[Reaction:R-RNO-1678923] TLR folding by chaperones GP96 and CNPY3
(inferredTo)	[Complex:R-HSA-1679076] ATP-bound Gp96 dimer:CNPY3:TLR7/8/9 [endoplasmic reticulum membrane]

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