Reactome | PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane]

catalystActivities	[CatalystActivity:10115102] serine-type endopeptidase activity of PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-159013] PI-PLAUR:PLAU(21-177):PLAU(179-431):SERPINE1 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-159005] urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR - Rattus norvegicus [Reaction:R-RNO-159001] urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10115101
displayName	PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane]
hasComponent	[Complex:R-RNO-158928] PLAU(21-177):PLAU(179-431) [plasma membrane] [EntityWithAccessionedSequence:R-RNO-158946] Plaur [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-158969] PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane] - Homo sapiens
maxDepth	3
name	PI-PLAUR:PLAU(21-177):PLAU(179-431)
producedByEvent	[Reaction:R-RNO-158942] urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-158969
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-159005] urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR [Reaction:R-RNO-159001] urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR
(hasComponent)	[Complex:R-RNO-159013] PI-PLAUR:PLAU(21-177):PLAU(179-431):SERPINE1 [plasma membrane] [Complex:R-RNO-159009] PI-PLAUR:PLAU(21-177):PLAU(179-431):SERPINE1:SERPINB2 [plasma membrane]
(physicalEntity)	[CatalystActivity:10115102] serine-type endopeptidase activity of PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane]
(output)	[Reaction:R-RNO-158942] urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR
(inferredTo)	[Complex:R-HSA-158969] PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane]

PI-PLAUR:PLAU(21-177):PLAU(179-431) [plasma membrane] Show undefined attributes

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