Reactome | Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation

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Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10114619
displayName	Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation
eventOf	[Pathway:R-RNO-72649] Translation initiation complex formation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-156823] Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation - Homo sapiens
input	[Complex:R-RNO-72571] 43S complex [cytosol] [Complex:R-RNO-156809] Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] [EntityWithAccessionedSequence:R-RNO-72557] Eif1ax [cytosol] [EntityWithAccessionedSequence:R-RNO-156803] Pabpc1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation
output	[Complex:R-RNO-156804] 43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] [EntityWithAccessionedSequence:R-RNO-72557] Eif1ax [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-156808
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-RNO-156823] Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA
(hasEvent)	[Pathway:R-RNO-72649] Translation initiation complex formation
(inferredTo)	[Reaction:R-HSA-156808] Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation

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