Reactome | Polo-like kinase mediated events

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Polo-like kinase mediated events Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222651
displayName	Polo-like kinase mediated events
eventOf	[Pathway:R-RNO-69275] G2/M Transition - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:171508] regulation of cell cycle
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-156699] Inactivation of Wee1 kinase - Rattus norvegicus [Reaction:R-RNO-156678] Activation of Cdc25C - Rattus norvegicus [Reaction:R-RNO-162657] Inactivation of Myt1 kinase - Rattus norvegicus [Reaction:R-RNO-4088130] PLK1 binds FOXM1 - Rattus norvegicus [Reaction:R-RNO-4088134] PLK1 phosphorylates FOXM1 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-156711] Polo-like kinase mediated events - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Polo-like kinase mediated events
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-156711
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-69275] G2/M Transition
(inferredTo)	[Pathway:R-HSA-156711] Polo-like kinase mediated events

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