Reactome | PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)

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PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) Show undefined attributes

catalystActivity	[CatalystActivity:10155603] glycerophospholipid phospholipase A1 activity of PLA2G [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10155605
displayName	PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)
eventOf	[Pathway:R-RNO-1482925] Acyl chain remodelling of PG - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1482546] 2-acyl LPG is acylated to PG by CRLS1 (IM) - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1482847] PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) - Homo sapiens
input	[SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-1524042] PG [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)
output	[SimpleEntity:R-ALL-1524047] 2-acyl LPG [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524085] LCFA(-) [mitochondrial inner membrane]
precedingEvent	[Reaction:R-RNO-1482546] 2-acyl LPG is acylated to PG by CRLS1 (IM) - Rattus norvegicus [Reaction:R-RNO-1482689] 1-acyl LPG is acylated to PG by CRLS1 (IM) - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1482847
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1482925] Acyl chain remodelling of PG
(precedingEvent)	[Reaction:R-RNO-1482546] 2-acyl LPG is acylated to PG by CRLS1 (IM)
(inferredTo)	[Reaction:R-HSA-1482847] PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM)

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