Reactome | PKC alpha interacts with and phosphorylates KIT

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PKC alpha interacts with and phosphorylates KIT Show undefined attributes

catalystActivity	[CatalystActivity:10153408] calcium,diacylglycerol-dependent serine/threonine kinase activity of PRKCA [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10153410
displayName	PKC alpha interacts with and phosphorylates KIT
eventOf	[Pathway:R-RNO-1433559] Regulation of KIT signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1433508] PKC alpha interacts with and phosphorylates KIT - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-RNO-197662] KIT [plasma membrane] [EntityWithAccessionedSequence:R-RNO-58196] PRKCA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PKC alpha interacts with and phosphorylates KIT
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-RNO-1433473] p-KIT (S741,746):PKC alpha [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1433508
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1433559] Regulation of KIT signaling
(inferredTo)	[Reaction:R-HSA-1433508] PKC alpha interacts with and phosphorylates KIT

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