Reactome | NRG1/2:ERBB3 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-1247502] NRG1/2:ERBB3:ERBB2 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-1977955] ERBB4:ERBB3 heterodimer [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-1977958] ERBB4 forms heterodimers with ERBB3 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10152153
displayName	NRG1/2:ERBB3 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-372885] ERBB3-1 [plasma membrane] [DefinedSet:R-RNO-1227956] NRG1/2 [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-1247495] NRG1/2:ERBB3 [plasma membrane] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-RNO-1963571] Ligand-Activated EGFR/ERBB3/ERBB4 [plasma membrane] - Rattus norvegicus
name	NRG1/2:ERBB3
producedByEvent	[Reaction:R-RNO-1247497] ERBB3 binds neuregulins - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1247495
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-1977958] ERBB4 forms heterodimers with ERBB3
(hasComponent)	[Complex:R-RNO-1977955] ERBB4:ERBB3 heterodimer [plasma membrane] [Complex:R-RNO-1247502] NRG1/2:ERBB3:ERBB2 [plasma membrane] [Complex:R-RNO-1810433] NRG1/2:ERBB3:p-Y877-ERBB2 [plasma membrane]
(output)	[Reaction:R-RNO-1247497] ERBB3 binds neuregulins
(hasMember)	[DefinedSet:R-RNO-1963571] Ligand-Activated EGFR/ERBB3/ERBB4 [plasma membrane]
(inferredTo)	[Complex:R-HSA-1247495] NRG1/2:ERBB3 [plasma membrane]