Reactome | RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm]

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RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-71307] RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] - Rattus norvegicus [Complex:R-RNO-5578688] AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] - Rattus norvegicus [Complex:R-RNO-6814541] RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) - Rattus norvegicus [BlackBoxEvent:R-RNO-6781818] RNA Pol II initiates transcription from damaged DNA template - Rattus norvegicus [Reaction:R-RNO-5578742] AGO1,2:small RNA complexes interact with chromatin - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10107940
displayName	RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-RNO-63537] Ghost homologue of POLR2K [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63502] Polr2a [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63504] Polr2b [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63506] Polr2c [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63508] POLR2D [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83713] Polr2e [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83714] Polr2f [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63517] Polr2g [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63523] Polr2h [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63525] POLR2I [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63531] Polr2j [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83715] POLR2L [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-113401] RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] - Homo sapiens
maxDepth	2
name	RNA Polymerase II holoenzyme complex (unphosphorylated)
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-113401
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) [BlackBoxEvent:R-RNO-6781818] RNA Pol II initiates transcription from damaged DNA template [Reaction:R-RNO-5578742] AGO1,2:small RNA complexes interact with chromatin
(hasComponent)	[Complex:R-RNO-6814541] RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] [Complex:R-RNO-5578688] AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] [Complex:R-RNO-71307] RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
(activeUnit)	[CatalystActivity:10109543] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-113401] RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm]

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