Reactome | thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP]

Schema > Reaction > Entries

thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] Show undefined attributes

catalystActivity	[CatalystActivity:10112305] pentosyltransferase activity of TYMP dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10112307
displayName	thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP]
eventOf	[Pathway:R-RNO-73621] Pyrimidine catabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-112265] thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] - Homo sapiens
input	[SimpleEntity:R-ALL-29372] Pi [cytosol] [DefinedSet:R-ALL-500444] Thy-Rib, dU [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] thymidine + phosphate => 2-deoxy-alpha-D-ribose 1-phosphate + thymine 2'-deoxyuridine + phosphate => 2-deoxy-alpha-D-ribose 1-phosphate + uracil
output	[SimpleEntity:R-ALL-112032] dRibP [cytosol] [DefinedSet:R-ALL-500438] Thy, Ura [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-112265
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-73621] Pyrimidine catabolism
(inferredTo)	[Reaction:R-HSA-112265] thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP]

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