Reactome | GRB10:INSR [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10108340
displayName	GRB10:INSR [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-110009] Grb10 [cytosol] [Complex:R-RNO-74678] Insulin:p-6Y-Insulin receptor [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-110010] GRB10:INSR [plasma membrane] - Homo sapiens
maxDepth	5
name	GRB10:INSR
negativelyRegulates	[NegativeRegulation:10108343] Negative regulation by 'GRB10:INSR [plasma membrane]'
producedByEvent	[Reaction:R-RNO-110011] Binding of Grb10 to the insulin receptor - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-110010
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-RNO-110011] Binding of Grb10 to the insulin receptor
(regulator)	[NegativeRegulation:10108343] Negative regulation by 'GRB10:INSR [plasma membrane]'
(inferredTo)	[Complex:R-HSA-110010] GRB10:INSR [plasma membrane]

Cite Us!