Reactome | RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]

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RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] - Rattus norvegicus [Complex:R-RNO-113722] Aborted elongation complex after arrest [nucleoplasm] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10105948
displayName	RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-RNO-63537] Ghost homologue of POLR2K [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-113420] phospho-Polr2a [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63504] Polr2b [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63506] Polr2c [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63508] POLR2D [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83713] Polr2e [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83714] Polr2f [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63517] Polr2g [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63523] Polr2h [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63525] POLR2I [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-63531] Polr2j [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83715] POLR2L [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-109909] RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] - Homo sapiens
maxDepth	2
name	RNA Polymerase II holoenzyme complex (hyperphosphorylated)
producedByEvent	[Reaction:R-RNO-113429] Elongating transcript encounters a lesion in the template - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-109909
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-RNO-113429] Elongating transcript encounters a lesion in the template
(hasComponent)	[Complex:R-RNO-113722] Aborted elongation complex after arrest [nucleoplasm] [Complex:R-RNO-6781822] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-RNO-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] [Complex:R-RNO-113425] RNA Polymerase II holoenzyme complex (hyperphosphorylated):TFIIF complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-109909] RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm]

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