Reactome | p-Y185,Y187 MAPK1 dimer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10123480
displayName	p-Y185,Y187 MAPK1 dimer [nucleoplasm]
hasComponent	2 × [EntityWithAccessionedSequence:R-RNO-112354] phospho-p-T185,Y187-MAPK1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-109856] p-Y185,Y187 MAPK1 dimer [nucleoplasm] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-RNO-199878] p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] - Rattus norvegicus [DefinedSet:R-RNO-198701] p-T,Y MAPK dimers [nucleoplasm] - Rattus norvegicus
name	p-Y185,Y187 MAPK1 dimer
positivelyRegulates	[PositiveRegulation:10211535] Positive regulation by 'p-Y185,Y187 MAPK1 dimer [nucleoplasm]'
producedByEvent	[BlackBoxEvent:R-RNO-9632910] ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-109856
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[PositiveRegulation:10211535] Positive regulation by 'p-Y185,Y187 MAPK1 dimer [nucleoplasm]'
(output)	[BlackBoxEvent:R-RNO-9632910] ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus
(hasMember)	[DefinedSet:R-RNO-199878] p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] [DefinedSet:R-RNO-198701] p-T,Y MAPK dimers [nucleoplasm]
(inferredTo)	[Complex:R-HSA-109856] p-Y185,Y187 MAPK1 dimer [nucleoplasm]