Reactome | DOCKs bind to RhoGEFs

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10150799
displayName	DOCKs bind to RhoGEFs
eventOf	[Pathway:R-RNO-983231] Factors involved in megakaryocyte development and platelet production - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1011598] DOCKs bind to RhoGEFs - Homo sapiens
input	[CandidateSet:R-RNO-1012978] DOCK-GEFs [cytosol] [DefinedSet:R-RNO-1012988] RAC1, CDC42 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	DOCKs bind to RhoGEFs
output	[Complex:R-RNO-1012969] DOCK-GEFs:RAC1, CDC42 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1011598
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-983231] Factors involved in megakaryocyte development and platelet production
(inferredTo)	[Reaction:R-HSA-1011598] DOCKs bind to RhoGEFs