Reactome | DHODH:FMN binds DHODH inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:70101] cytosol
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11126062
displayName	DHODH:FMN binds DHODH inhibitors
eventOf	[Pathway:R-PFA-500753] Pyrimidine biosynthesis - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9708759] DHODH:FMN binds DHODH inhibitors - Homo sapiens
input	[CandidateSet:R-ALL-9708729] DHODH inhibitors [cytosol] [Complex:R-PFA-73534] DHODH:FMN [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	DHODH:FMN binds DHODH inhibitors
output	[Complex:R-PFA-9708760] DHODH:FMN:DHODH inhibitors [mitochondrial inner membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-9708759
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-500753] Pyrimidine biosynthesis
(inferredTo)	[Reaction:R-HSA-9708759] DHODH:FMN binds DHODH inhibitors

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