Reactome | OAS antiviral response

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11129200
displayName	OAS antiviral response
eventOf	[Pathway:R-PFA-1169410] Antimicrobial mechanism of IFN-stimulated genes - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:172355] defense response to virus
hasDiagram	true
hasEHLD	false
hasEvent	[Depolymerisation:R-PFA-9009950] PDE12 cleaves 2'-5' oligoadenylates - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-8983711] OAS antiviral response - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	OAS antiviral response
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-8983711
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-1169410] Antimicrobial mechanism of IFN-stimulated genes
(inferredTo)	[Pathway:R-HSA-8983711] OAS antiviral response

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