Reactome | Glutamate and glutamine metabolism

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Glutamate and glutamine metabolism Show undefined attributes

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128128
displayName	Glutamate and glutamine metabolism
eventOf	[Pathway:R-PFA-71291] Metabolism of amino acids and derivatives - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9910493] L-amino acid metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-PFA-70666] glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] - Plasmodium falciparum [Reaction:R-PFA-70654] ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] - Plasmodium falciparum [Reaction:R-PFA-70664] PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro - Plasmodium falciparum [Reaction:R-PFA-6783939] PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro - Plasmodium falciparum [Reaction:R-PFA-6783955] PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro - Plasmodium falciparum [Reaction:R-PFA-70613] GOT2 transaminates OA and L-Glu - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-8964539] Glutamate and glutamine metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Glutamate and glutamine metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-8964539
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-71291] Metabolism of amino acids and derivatives
(inferredTo)	[Pathway:R-HSA-8964539] Glutamate and glutamine metabolism

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