Reactome | Pentose phosphate pathway

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Pentose phosphate pathway Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128108
displayName	Pentose phosphate pathway
eventOf	[Pathway:R-PFA-71387] Metabolism of carbohydrates and carbohydrate derivatives - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:15013] pentose-phosphate shunt
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-PFA-70377] G6PD multimers dehydrogenate G6P - Plasmodium falciparum [Reaction:R-PFA-71303] RPE dimers isomerise RU5P to XY5P - Plasmodium falciparum [Reaction:R-PFA-199803] RPE dimers isomerize XY5P to RU5P - Plasmodium falciparum [Reaction:R-PFA-6787329] PGM2:Mg2+ isomerises R1P to R5P - Plasmodium falciparum [Reaction:R-PFA-8982667] PGM2:Mg2+ isomerises dR1P to dR5P - Plasmodium falciparum [Pathway:R-PFA-73843] 5-Phosphoribose 1-diphosphate biosynthesis - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-71336] Pentose phosphate pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Pentose phosphate pathway Pentose phosphate pathway (hexose monophosphate shunt)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-71336
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-71387] Metabolism of carbohydrates and carbohydrate derivatives
(hasEncapsulatedEvent)	[Pathway:R-PFA-70326] Glucose metabolism [Pathway:R-PFA-8956319] Nucleotide catabolism
(inferredTo)	[Pathway:R-HSA-71336] Pentose phosphate pathway

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