Reactome | Ion influx/efflux at host-pathogen interface

Schema > Pathway > Entries

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128648
displayName	Ion influx/efflux at host-pathogen interface
eventOf	[Pathway:R-PFA-6803157] Antimicrobial peptides - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-PFA-435171] NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-6803544] Ion influx/efflux at host-pathogen interface - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Ion influx/efflux at host-pathogen interface
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-6803544
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-6803157] Antimicrobial peptides
(inferredTo)	[Pathway:R-HSA-6803544] Ion influx/efflux at host-pathogen interface

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