Reactome | SUMOylation of TOP2B with SUMO1

Schema > Reaction > Entries

SUMOylation of TOP2B with SUMO1 Show undefined attributes

catalystActivity	[CatalystActivity:11117364] SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11117602
displayName	SUMOylation of TOP2B with SUMO1
eventOf	[Pathway:R-PFA-4615885] SUMOylation of DNA replication proteins - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:4162] protein sumoylation
inferredFrom	[Reaction:R-HSA-4641345] SUMOylation of TOP2B with SUMO1 - Homo sapiens
input	[Complex:R-PFA-2993783] SUMO1:C93-UBE2I [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-4641359] TOP2B [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	SUMOylation of TOP2B with SUMO1
output	[EntityWithAccessionedSequence:R-PFA-4641297] monoSUMO1-K-TOP2B [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-912481] UBE2I [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-4641345
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-4615885] SUMOylation of DNA replication proteins
(inferredTo)	[Reaction:R-HSA-4641345] SUMOylation of TOP2B with SUMO1

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