Reactome | p-S256-Aquaporin-2 passively transports water into cell

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p-S256-Aquaporin-2 passively transports water into cell Show undefined attributes

catalystActivity	[CatalystActivity:11113860] water channel activity of p-S256-AQP2 tetramer [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11113862
displayName	p-S256-Aquaporin-2 passively transports water into cell
eventOf	[Pathway:R-PFA-432040] Vasopressin regulates renal water homeostasis via Aquaporins - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-PFA-445714] Aquaporin-3 passively transports water out of cell - Plasmodium falciparum [Reaction:R-PFA-432067] Aquaporin-4 passively transports water out of cell - Plasmodium falciparum
inferredFrom	[Reaction:R-HSA-432065] p-S256-Aquaporin-2 passively transports water into cell - Homo sapiens
input	[SimpleEntity:R-ALL-109276] H2O [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	p-S256-Aquaporin-2 passively transports water into cell
output	[SimpleEntity:R-ALL-29356] H2O [cytosol]
precedingEvent	[Reaction:R-PFA-432054] Aquaporin-1 passively transports water out of cell - Plasmodium falciparum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-432065
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-432040] Vasopressin regulates renal water homeostasis via Aquaporins
(precedingEvent)	[Reaction:R-PFA-445714] Aquaporin-3 passively transports water out of cell [Reaction:R-PFA-432067] Aquaporin-4 passively transports water out of cell
(inferredTo)	[Reaction:R-HSA-432065] p-S256-Aquaporin-2 passively transports water into cell

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