Reactome | Dopamine clearance from the synaptic cleft

Schema > Pathway > Entries

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128584
displayName	Dopamine clearance from the synaptic cleft
eventOf	[Pathway:R-PFA-112311] Neurotransmitter clearance - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-PFA-379393] SLC6A3 cotransports DA, Na+, Cl- from extracellular region to cytosol - Plasmodium falciparum [Reaction:R-PFA-9714580] SLC6A3 binds DRIs - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-379401] Dopamine clearance from the synaptic cleft - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Dopamine clearance from the synaptic cleft Clearance of dopamine
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-379401
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-112311] Neurotransmitter clearance
(inferredTo)	[Pathway:R-HSA-379401] Dopamine clearance from the synaptic cleft

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