Reactome | ABCB11 transports bile salts from cytosol to extracellular region

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ABCB11 transports bile salts from cytosol to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:11112439] ABC-type bile acid transporter activity of ABCB11 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11112441
displayName	ABCB11 transports bile salts from cytosol to extracellular region
eventOf	[Pathway:R-PFA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-193362] ABCB11 transports bile salts from cytosol to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-ALL-193416] bile salts [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ABCB11 transports bile salts from cytosol to extracellular region Transport (efflux) of bile salts by ABCB11 (bile salt export pump)
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-ALL-193479] bile salts [extracellular region] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-193362
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-193368] Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol [Pathway:R-PFA-159418] Recycling of bile acids and salts
(inferredTo)	[Reaction:R-HSA-193362] ABCB11 transports bile salts from cytosol to extracellular region

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