Reactome | Activation of AKT2

Schema > Pathway > Entries

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128256
displayName	Activation of AKT2
eventOf	[Pathway:R-PFA-109704] PI3K Cascade - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:262292] positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-PFA-109701] PDPK1 binds PIP3 - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-165158] Activation of AKT2 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activation of AKT2 Activation of PKB
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-165158
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-109704] PI3K Cascade
(inferredTo)	[Pathway:R-HSA-165158] Activation of AKT2

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